NAD+ Forums

Wikipedia, sometimes correct, states that cx43 is detected in MOST cell types, including heart muscle cells. Here's my point again: Sinclair may be misleading us. I use intranasal NAD+ and consider it the most efficacious for the money. But if Sinclair is correct, then I and other NAD+ customers are...

Sinclair said that since NAD is too large to pass through a cell membrane, only precursors like NR and NMN are efficacious. All the responses to my post said that this is true except maybe in a very small number of tissue types. I can only conclude that increasing exogenous NAD would be futile for m...

So, Alive By Nature needs to close down its NAD IV Clinic as a fraud and stop selling sublingual and intranasal NAD+ for the same reason?!?!

I just read a Facebook post by David Sinclair stating that NAD+ is too large to pass through a cell's membrane and thus only smaller precursors are effective. I thought that there was plenty of evidence that endogenous NAD+ enters the cell. What's true?

Nuchida is claiming that NAD is too large to enter a cell and that taking NAD+ by ANY route is therefore useless. https://nuchido.com/blogs/articles/we-need-a-new-way-to-boost-nad?mc_cid=04b6113fd5&mc_eid=a78acebbc0 My research indicates that this is not totally correct: Connexin 43 is a transporter...