Search found 30 matches

by nettlesbe
Thu Sep 12, 2019 10:58 am
Forum: NAD+
Topic: NAD+ IV increases NAD+ levels in blood plasma 400% in humans
Replies: 12
Views: 12122

Re: NAD+ IV increases NAD+ levels in blood plasma 400% in humans

Very surprising that they found NO increase in blood plasma levels of NAD+ for the first 2hours. It seems approximately 250 mg is taken up by tissues, or red blood cells before any excess shows up in blood plasma. Certainly disproves the idea that NAD+ is trapped in the blood and not readily useful ...
by nettlesbe
Thu Sep 12, 2019 10:51 am
Forum: NAD+
Topic: NAD+ IV increases NAD+ levels in blood plasma 400% in humans
Replies: 12
Views: 12122

NAD+ IV increases NAD+ levels in blood plasma 400% in humans

This study was just published that documented changes in plasma and urine levels of NAD+ and its metabolites during and after 750 mg NAD+ intravenous (IV) infusion. A Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD+ Surpris...
by nettlesbe
Mon Sep 02, 2019 7:20 pm
Forum: Exercise
Topic: Multiple Ways to Increase NAD+ Levels
Replies: 20
Views: 23805

Re: Multiple Ways to Increase NAD+ Levels

I'm a recent convert to carbonated water to help with appetite control through the middle of the day.

MCT oil with some gelatin is even more effective for me, but of course a bit more trouble.

I carry a couple bottles of carbonated water with me everywhere now.
by nettlesbe
Sat Aug 31, 2019 5:12 pm
Forum: NAD+
Topic: Just Learning about NAD+
Replies: 15
Views: 17941

Re: Just Learning about NAD+

Here's the most detailed review of NAD+ research that I have found:

Role of NAD+ and related Precursors as Therapeutic Targets for
Age-related Degenerative Diseases: Rationale, Biochemistry,
Pharmacokinetics, and Outcomes

Nady Braidy, 2018

https://sci-hub.se/10.1089/ars.2017.7269
by nettlesbe
Tue Aug 27, 2019 9:09 pm
Forum: NR
Topic: Clinical study affirms Niagen nicotinamide riboside ingredient’s long-term safety, optimal dosing
Replies: 29
Views: 30130

Re: Clinical study affirms Niagen nicotinamide riboside ingredient’s long-term safety, optimal dosing

So why do we pay more for the "highly sought after" NMN if NR can enter the cell wall all on its own? Of course we all want whatever works. NR seems to have an advantage in crossing the cellular membrane more easily in some cell types. Chromadex says that means it is "better" and that NMN and NAD+ ...
by nettlesbe
Mon Aug 26, 2019 11:19 am
Forum: NR
Topic: New NR Study Released
Replies: 2
Views: 6295

Re: New NR Study Released

Yes, the inflammation decrease was a good sign. Too bad it all seems to be from NAD+, not NR.

Another post about this research :

NAD+ is the transport molecule used by the body, not NR

viewtopic.php?f=22&p=748#p748
by nettlesbe
Fri Aug 23, 2019 2:38 pm
Forum: NR
Topic: NAD+ is the transport molecule used by the body, not NR
Replies: 1
Views: 5089

NAD+ is the transport molecule used by the body, not NR

2 recent studies show that NR is never found at more than trace levels in the blood, and was not increased with supplementation. NR levels in humans do not increase after 3 weeks of 1,000 mg a day of oral NR supplements NR given to lactating mice does not reach the bloodstream https://i2.wp.com/ali...
by nettlesbe
Sun Aug 11, 2019 11:43 am
Forum: NMN
Topic: What's your NAD? How do you test?
Replies: 7
Views: 6572

Re: What's your NAD? How do you test?

There are no commercial providers of NAD+ testing.

We are working to provide this service at our NAD+ injection clinic in Ponte Vedra Beach Florida later this year, but the start date is not yet firmed up

https://alivebynature.com/clinic/
by nettlesbe
Tue Aug 06, 2019 1:44 pm
Forum: Nutrition
Topic: Nutrition science is broken. This new egg study shows why
Replies: 14
Views: 11746

Nutrition science is broken. This new egg study shows why

t’s been a tortuous path for the humble egg. For much of our history, it was a staple of the American breakfast — as in, bacon and eggs. Then, starting in the late 1970s and early 1980s, it began to be disparaged as a dangerous source of artery-clogging cholesterol, a probable culprit behind America...
by nettlesbe
Fri Jul 26, 2019 3:20 pm
Forum: FAQs
Topic: What is the recommended daily dosage of your products?
Replies: 8
Views: 13227

What is the recommended daily dosage of your products?

Recommended daily dosages of sublingual NMN and NAD+ are at least 400mg, which equates to 3-4 tablets per day at minimum (or 3-4 scoops if using PURE powders).

It is recommended to space out the daily dosages of NMN and NAD+ for optimal bioavailablity.