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NRH as a NAD+ precursor

Posted: Thu Apr 23, 2020 4:05 pm
by Fred
Maintaining cellular NAD levels through supplementation with intermediates of NAD synthesis has considerable health benefits. A new study demonstrates that the reduced form of nicotinamide riboside, NRH, can be converted to NAD in a biosynthetic pathway that involves adenosine kinase, thus strongly boosting NAD levels in cells and tissues.
https://www.nature.com/articles/s42255-020-0197-6

https://www.nature.com/articles/s42255-020-0194-9.pdf

Re: NRH as a NAD+ precursor

Posted: Mon Apr 27, 2020 5:19 pm
by jocko6889
Fred wrote:
Thu Apr 23, 2020 4:05 pm
Maintaining cellular NAD levels through supplementation with intermediates of NAD synthesis has considerable health benefits. A new study demonstrates that the reduced form of nicotinamide riboside, NRH, can be converted to NAD in a biosynthetic pathway that involves adenosine kinase, thus strongly boosting NAD levels in cells and tissues.
https://www.nature.com/articles/s42255-020-0197-6

https://www.nature.com/articles/s42255-020-0194-9.pdf
Very interesting, Fred. I found this youtube video that explains the newly discovered pathway found in the study. Worth a look.

https://www.youtube.com/watch?v=9nJl6EDFShc