Exercise ⇒ Exercise as senolytics

[AlbertY]

https://onlinelibrary.wiley.com/doi/10.1111/acel.13294

This is a systemic review paper that found:

Exercise can reduce the markers of senescent cells in healthy humans, while it lowered the markers of senescent cells in obese but not healthy animals. The discrepancy between human and animal studies may be due to the relatively small volume of research and the variations in markers of senescent cells, types of cells/tissues, and health conditions. These findings suggest that exercise has senolytic properties under certain conditions, which warrant further investigations.

[Newage]

Just one more of the many many benefits of exercise.
Sit on the couch and watch TV as the “bad cells” proliferate.

[NewLifeScience]

So certain forms of exercise ( i am thinking of cardio... or exercises that really work on your lean muscle mass) destroy inflammatory processes in your blood and tissue,

If it is also performing autophagy, then i really have stacked things up for clearing out inflammatory and cellular debris.

Now i just want all my hair to grow back like a Chia plant.

[Newage]

Also the boost of feel good endorphins released by exercise. The harder the effort the better you feel afterwards.

[smokinjoe]

So many senolytic opportunities.

I don't know if this is the same process, but i remember reading long ago that when endorphins are released, they essentially bathe the blood of inflammatory agents, like catecholamines (caused by stress).

normally i'd surf around looking for a study to back this up...  but not tonight! 

but i can tell from experience this is true. If I've had a stressful day, a run washes a lot of this away.

[jessicaP]

Even if i feel exhausted due to stress, once i am on the elliptical, i can do a full session.

Along with everything else i do, it is nice to know exercise has this same action, as well as flushing through the sweath glands and moving toxins through the lymph system.

[Newage]

Even if i feel exhausted due to stress, once i am on the elliptical, i can do a full session.

Along with everything else i do, it is nice to know exercise has this same action, as well as flushing through the sweath glands and moving toxins through the lymph system.

 

There are many hidden benefits to the body from exercise. It’s not only the obvious benefits but the ones that do not necessarily register at the time. Exercising at altitude for better performance at sea level is one example.