https://sci-hub.se/https://content.iosp ... /jad190444The risk of suffering from dementia was significantly lower for glucocorticoid users compared to non-users (HR = 0.81, CI = 0.78–0.84).
The lowest risk was found among users of inhaled glucocorticoid (HR = 0.65, CI = 0.57–0.75), followed by nasal (HR = 0.76, CI = 0.66–0.87), other (HR = 0.84, CI = 0.80–0.88), and oral users (HR = 0.83, CI = 0.78–0.88).
We found no difference in risk reduction between long- and short-term-users.
Conclusion: Longitudinal German health insurance data indicate that the use of glucocorticoids is associated with a lower risk of dementia. Prospective clinical trials will be necessary to determine whether glucocorticoids can have a positive impact on neuroinflammation and thus protect persons against dementia.
Miscellaneous Topics ⇒ Cortisone spray and asthma inhalators are associated with a lower risk of dementia
I am not surprised to see it may be related to anti-inflammatory processes.
I think one of our primary tasks in daily life is to be vigilant for anything in our bodies, from head to toe, that may be subject to regular inflammation.
https://news.berkeley.edu/2019/12/04/dr ... -dementia/