you can buy sprouting jars on amazon, which are about twice the size of a large mason jar. this is what I use and I have a continuous supply to use every day.
Wow this sounds like the perfect supplement,Vandevalk1 wrote: ↑Wed Nov 20, 2019 7:24 pmI grow my own. its cheap and very simple. Dr. Rhonda Patrick also recommends freezing them as this amplifies the abundance of sulforaphane even more so!NewLifeScience wrote: ↑Tue Nov 19, 2019 6:40 pmI hear you, 2 years can mean a LOT OF CHANGE..
but since the sprouts have like 100-500x that of regular broccoli, maybe growing them is a good way to consume them.
I have never heard of this substance before... but on this forum that list is growing
Liposomal Curcumin / Resveratrol
Melatonin 1mg (am)
Blueberry extract 1g
Vitamin E tocotrienols 50 mg
Astragalus 500 mg
Methyl B12 5000 mcg 3x/week
Methyl Folate 1000 mcg 1-3/week
Does NAM inhibit Sirt1? This paper argues that while it is an inhibitor invitro this imay not be the case invivo.
"once administered to cells, NAM is rapidly converted to NAD+ and, therefore, the cellular concentration of NAM decreases rapidly while that of NAD+ increases. The result would be an inhibition of SIRT1 for a limited duration, followed by an increase in the activity."
"To understand better the effects of cellular administration of NAM, we reviewed published literature in which treatment with NAM was used to inhibit SIRT1 and found that the expected inhibitory effect of NAM was either unreliable or muted in many cases. In addition, studies demonstrated NAM administration stimulates SIRT1 activity and improves the functions of cells and organs."
This says that while it is a sirt1 inhibitor at larger concentrations at 5mM it is an activator.
"In the cells pulsed with 5 mM NAM, cellular NAD+ concentration increased by close to 40% in 12 h, and this increase was maintained throughout the 21 days of the investigation."
"NAM at 5 mM but Not at Higher Concentrations Causes the Activation of SIRT1 and the Decrease of Mitochondrial Content"
"NAM at a 10 or 20 mM dose caused an increase of [NAD+] to the levels almost identical to that in the cells treated with 5 mM NAM but resulted in an inhibition of SIRT1 activity during the early time period."
It seems the sensible thing would be to aim for a concentration of 5mM.
I wonder how much more (or less) sulforaphane you can get from eating the sprouts vs taking the capsules? Anyone know?
The package stands a good chance of sitting there for a year undisturbed.
I will try to get to it..
NMN since June, 2019 (started at 250mg, 500mg as of Oct 1st)
NAD+ nasal spray since July, 2019
Resveratrol since Sept 2019
Astaxanthin 10mg since October 20th
Blueberry concentrate 500 mg since October 20th
Berberine 250 mg since October 20th
Some online sellers do have the product a little cheaper.
as far as supplement options, her favorite is Prostaphane (which you can only get in france (or ebay)) which is the only one that gives actual suforaphane.
Otherwise, she says to go with avmacol (which is a precursor) which has been used in the clinical trials